Compare the Mercedes E Class 500 W124 - [1990] vs Lexus IS 350 3.5 V6 - [2006]. Find out which car is the fastest, most powerful, lightest or has the biggest engine in our top trumps style comparison page. Find out which car has the highest top speed or is the fastest accelerating, is it the Mercedes E Class 500 W124 or the Lexus IS 350 3.5 V6. We'll leave it up to you to decide which is your favourite.